Abstract Topologically associating domains (TAD) are a key structure of the 3D mammalian genomes.However, the prevalence and dynamics of TAD-like domains in single cells remain elusive.Here we Goal Stick bag develop a new algorithm, named deTOKI, to decode TAD-like domains with single-cell Hi-C data.By non-negative matrix factorization, deTOKI seek
Introduction: This study employed surgical robot to perform anatomic single-bundle reconstruction using the modified transtibial (TT) technique and anteromedial (AM) portal technique.The purpose was to directly compare tunnel and graft characteristics of the two techniques.Methods: Eight cadaveric knees without ligament injury were used in the stud
Intensive development of South Yakutia, a mountainous area in the Russian sporadic permafrost zone, must be founded on knowledge about regional permafrost conditions.New permafrost maps for mountainous areas in South Yakutia (the Elkon Mountains and the Olekma-Chara Upland) are presented that provide a more detailed and updated description of perma
A system analysis and design of purple sweet potatoes instant porridge product development is design elements that interact using the system input of purple sweet potatoes as raw material which is operated by the stage of formulation, analysis, and optimization.The purpose of this research are determine the appropriate process parameters in produci
Trends in extreme precipitation Acne Care and their causes were analyzed for events within the Laurentian Great Lakes for several periods: 1908–2020, 1949–2020, 1980–2019, and 1980–2020.Upward trends in extreme precipitation were found for multiple metrics, including the number of exceedances of return period thresholds for several duration